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These drugs mimic the binding of the naturally produced GLP-1 hormone to its cognate receptor after food intake, which has the effect of regulating glucose homeostasis, lipid metabolism, gastric emptying and feelings of satiety 19 (Figure 1)

A typical dose is 300 mcg to 600 mcg once daily, given as a subcutaneous injection, often in the abdomen

A retrospective single-center study

During lactation, the RDA is 2.8 mcg

Additionally, while the most common side effect was mild to moderate gastrointestinal upset, there were fewer events per 100 patients across all of the cagrilintide treatment groups in comparison to the subjects receiving 3.0 mg of liraglutide [1]