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Triggering a Chain Reaction Once attached, it sets off a biochemical chain reaction, increasing cyclic adenosine monophosphate (cAMP) levels

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These released exosomes can then modulate immune response in other cells through a payload of inflammatory cytokines, like TNF-alpha, or through microRNA s that decrease inflammation.[ref] Mast cell release of exosomes has been shown to increase the formation of collagen in fibroblasts, which can lead to fibrosis (including pulmonary fibrosis, IPF)

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