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In addition to cochlear effects, quinine has been associated with vestibular toxicity, resulting in balance disturbances and dizziness (Semedo et al
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Skin reactions can include flushing or generalised itching
Enhanced collagen production and accumulation by smooth muscle cells
It has been established that elevated levels of SLC1A5-AS bind directly to myeloid zinc finger 1 (MZF1), thereby acting as a transcriptional deterrent and reducing its binding to the SLC1A5 promoter region
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