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Contrary to the beneficial findings in basic studies, where GLP-1 analogs could alleviate metabolic lesions in the retina's parenchyma or vessel bed and demonstrate neural protective effects, the discrepancy between preclinical results and real-world practice has sparked safety concerns about expanding their use

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Depletion in vitro of mitochondrial glutathione in rat hepatocytes and enhancement of lipid peroxidation by Adriamycin and 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU) Biochem Pharmacol , 32:13831388

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