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Particulate formation also suggests the bacteriostatic water was contaminated before reconstitution, the vial seal was compromised, or non-sterile technique was used during dose draws

In order to reduce the incidence of injection site reactions, it is recommended to rotate the site of injection to different areas of the abdomen

This research was funded by National Natural Science Foundation of China, grant number 82560147, Health Commission Science and Technology Fund Project of Guizhou Province, grant number gzwkj2025279 and Xiangshan Talent Project of Zhuhai Peoples Hospital, grant number 2023XSYC-02

Pekala J et al

Bacteriostatic water may not be readily available in easy locations to purchase