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To investigate the role of C32E8.9 under this condition, we assessed the mobility of GMC101 worms treated with doxycycline in combination with C32E8.9 RNAi (Supplementary Fig

These studies would help identify critical periods for intervention and the persistence of early digital behavior effects

The power to detect differences between the study groups is larger than what is projected here as we will measure most of the outcomes more than once and also use these repeated measurements in the same analyses, adjusting for interdependence within a child using mixed effects models, generalised estimating equations or other appropriate methods

If the half-life is genuinely under 30 minutes, the compound is cleared too rapidly