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In dermal wound models using full-thickness punch wounds in mice and rats, topical application (5-50 g per wound) accelerated closure, enhanced collagen deposition, and promoted angiogenesiseffects maintained even in diabetic, aged, or corticosteroid-suppressed animals

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Its National Institutes of Health (NIH) research funding portfolio is the second largest among U.S

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Involvement of the oral cavity (caf au lait pigmentation) is rare