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Liver: Administer under strict medical supervision in patients with liver impairment
However, this strategy is only attractive if the therapeutic agent itself is not a substrate for CPA, or if the case, that its functional activity is not negatively affected by C-terminal cleavage
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Intracellular metabolites (GSH, glucose, glucose-6P, pyruvate, succinate) were measured by liquid chromatography (Vanquish HPLC Thermo Scientific) coupled to high resolution mass spectrometry (QExactive HF Thermo Scientific)
We don't need to remind our readers that regardless of what diet you choose , a high protein:energy ratio must be maintained - above all else
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