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While there is some existing research on berberine as a standalone supplement, the evidence doesn't support the idea that it works as effectively as a prescription GLP-1 medication , and studies on the transdermal delivery method (absorbing supplements through the skin) for these ingredients are lacking

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Peptides are largely broken down by digestive enzymes in the gut, meaning oral supplements may have little or no physiological effect

The formula includes an added component of Pyridoxine (Vitamin B6), which is compounded with the active ingredient by licensed pharmacies to help mitigate common gastrointestinal side effects and support energy metabolism