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Harmon C, Robinson MW, Fahey R, Whelan S, Houlihan DD, Geoghegan J, et al
The body needs approximately 15 mg/day from a combination of dietary sources and endogenous synthesis [1]
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It also boosts antioxidant defenses like SOD and GSH, thereby limiting oxidative stress
Beyond hormonal changes, several interconnected factors may contribute to perimenopausal weight gain: Metabolic slowdown : Basal metabolic rate naturally decreases with age, meaning the body burns fewer calories at rest Muscle mass loss : Sarcopenia (age-related muscle loss) accelerates during perimenopause, further reducing metabolic rate Sleep disruption : Night sweats and insomnia, common perimenopausal symptoms, interfere with hormones regulating appetite and glucose metabolism Mood changes : Anxiety, depression, and stress during this transition may lead to emotional eating patterns Reduced physical activity : Fatigue, joint pain, and other symptoms may decrease exercise tolerance Research suggests women may gain weight gradually during perimenopause, though individual experiences vary considerably
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