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What the Research Shows The robust weight-management evidence the STEP trials for semaglutide and the SURMOUNT trials for tirzepatide, where participants lost roughly 15% and 21% of body weight respectively comes from injectable formulations, not patches

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The same medication that can cause allodynia in some patients at higher doses appears to treat neuropathic pain in others through anti-inflammatory mechanisms

Semaglutide GLP-1 is also not recommended for individuals with a history of severe gastrointestinal disease or gastroparesis, as it may exacerbate these conditions