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In 2020, it became the only diabetic drug to be approved for reducing or preventing the risk of major cardiovascular events (MACE) in patients with type 2 diabetes
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This included Israel Simon Kleiner and Samuel Meltzer, two American physiologists, based at the Rockefeller University in New York who in 1915 demonstrated with animal experiments the power of intravenously administered pancreatic extracts in lowering blood sugar
The convenience of a weekly injection also contributes to their appeal
Hoel et al., 2021
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