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Although Bcr-Abl inhibitors such as imatinib, nilotinib, and dasatinib are effective in CML therapy 7,8,9 , the acquisition of the T315I mutation of BCR-ABL in patients causes the resistance to most tyrosine kinase inhibitors (TKI), leading to poor outcomes

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Any retatrutide being offered outside of a regulated clinical trial in the UK is unlicensed, and its quality, safety, and efficacy cannot be guaranteed

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