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The pivotal STEP trials for semaglutide and SURMOUNT trials for tirzepatide included thousands of participants with monitoring for suicidal ideation using standardized tools such as the Columbia-Suicide Severity Rating Scale (C-SSRS), and did not demonstrate elevated rates compared to placebo groups
There is no scientific data to support any dosage claims made by weight-loss clinics
Weight Loss and Metabolic Health For many women, weight loss is the most noticeable benefit of semaglutide
However, it has been shown to be helpful for the treatment of depression, panic disorder, polycystic ovarian syndrome, and fatty liver
By slowing down the stomachs emptying process, GLP-1s prolong the feeling of fullness
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