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This discouraged the pharmaceutical industry from developing such drugs and undermined the FDA's willingness to approve them
Int J Sports Med 1996;17(5):320-324
9,353,354,355 Specifically, the increased gluconeogenesis and decreased glycogen synthesis in hepatic IR results in fasting hyperglycemia that increases total TG levels and blood pressure (BP), reduces HDL-C levels, and increases the risk of thrombosis formation
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