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Bifunctional PEGylated exenatide-amylinomimetic hybrids to treat metabolic disorders: an example of long-acting dual hormonal therapeutics
To increase the therapeutic effectiveness of GLP-1 in people with type 2 diabetes mellitus (T2DM), attempts have been made to prolong its half-life in the body
Even brief sessions (1520 minutes) can provide benefits
50% of patients stop using the drugs after year one, and 85% fall off after year two
If transaminase levels increase, repeat the LFTs and monitor until these normalise
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