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As of a July 2024 survey, among the states providing coverage, 11 required prior authorization, and 11 had policies tying coverage to body mass indices
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The substantial increase in plasma bile acid concentrations (primary, secondary, total and unconjugated bile acid concentrations) with metformin may be explained by the fact that metformin increased the abundance of probiotic bacteria, especially Lactobacillus , and thus their bile salt hydrolase (BSH) gene expression
Others may have infrequent but severe complications like gallbladder problems, enlarged thyroid, or allergies
Ortiz-AndrellucchiASnchez-VillegasARodrguez-GallegoCLemesAMoleroTSoriaAet al (2008)
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