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In practice, most people continue increasing gradually until they reach a dose that feels both effective and sustainableup to 15 mg once weekly

Many of the traditional oral antihyperglycemic agents (e.g

In particular, Witschi et al

Within the first week or two, some individuals may notice slight changes, such as feeling fuller more quickly or a mild reduction in appetite, but these effects typically become more pronounced as the dose is gradually increased

Contact a doctor if bright yellow urine persists, appears with other symptoms like fatigue or nausea, or occurs with urinary changes such as pain, blood, or unusual smell or consistency