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In line with the KPCY model, RETA effectively reduced body weights within the first two weeks, plateauing at 41% loss of baseline body weight (Fig

These medications provide effective glycaemic control, significant weight reduction, and cardiovascular protection through complex signalling pathways affecting pancreatic, gastrointestinal, neural, and cardiovascular tissues

While both options can support meaningful weight loss, they do so through different mechanisms and tend to benefit different patient profiles

23 American Diabetes Association

These GLP-1 receptor agonists work by mimicking the hormone glucagon-like peptide-1 to regulate appetite, digestion, and blood sugar, but may cause side effects like nausea, diarrhea, or constipation, which are typically mild and improve over time