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The hormone boost from surgery fades
It is a synthetic fragment of human growth hormone (amino acids 176-191), studied in research settings for its proposed role in fat metabolism
Specifically, they evaluated the safety profile and efficacy of 50 mg of semaglutide, an oral glucagon-like peptide-1 analog, versus placebo in adults with a body mass index (BMI) between 27 and 30 kg/m 2 , bodyweight-related health issues, or comorbidities, but not T2D
Adults aged 18 years with a body mass index (BMI) of at least 30 kg/m 2 or a BMI of at least 27 kg/m 2 with at least 1 body weight-related comorbidity and 1 self-reported dietary weight-loss effort were randomly assigned, 1:1, to receive oral semaglutide 50 mg or placebo once per day for 68 weeks as an adjunct to lifestyle intervention
ASH 2011
