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In contrast, GABA, the main inhibitory neurotransmitter, induces hyperpolarization and dampens excessive neuronal activity, thus maintaining stability within neural networks
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PMID: 98 PuppeJSeifertTEichlerCPilchHMallmannPMalterW
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The GPR30 receptor agonist G1 inhibits ferroptosis and significantly improves chondrocyte viability and motor ability in mice through the YAP1/FTH1 pathway, while GPR30 receptor antagonist G15 has the opposite effect, suggesting that hormone-related ferroptosis may emerge as a promising target for alleviating osteoarthritis in postmenopausal women
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