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Exercise capacity was determined by a single maximal exercise test to voluntary fatigue on a motorized treadmill (Exer 3/6, Columbus Instruments) in females [Young ( n = 10), Old Con ( n = 17), and Old mAb ( n = 22)] and males [Young ( n = 10), Old Con ( n = 9), and Old mAb ( n = 9)]
Much of this work has been performed in laboratory or animal models
Pineda-Pampliega et al
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A formal FDA decision will likely not come for several months.
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