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The pivotal trials for both diabetes and weight management (SUSTAIN and STEP programs) excluded pregnant women and required contraception during participation, limiting our understanding of fertility effects
J Toxicol Clin Toxicol 2000, 38: 219-220
The American Diabetes Association (ADA) Standards of Care and American College of Physicians (ACP) guidelines support the use of GLP-1 receptor agonists, including dual agonists like tirzepatide, as effective options for glycemic control and weight management
Hybrid antibiotics with the nikkomycin nucleoside and polyoxin peptidyl moieties
Active liver disease or gallbladder problems : GLP-1 use has been linked to gallstone formation in some patients
