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It is taken up intact by chylomicrons in the gut
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Likewise, the NLRP3-specific inhibitor MCC950 effectively reduces IL-1 release induced by bacterial lipopolysaccharides, providing an additional means to limit excessive inflammasome activation and cytokine storm ( 4 Fungal-induced mitochondrial damage mechanisms Fungal pathogens, ranging from opportunistic yeasts such as Candida albicans to filamentous species like Aspergillus fumigatus , impose substantial burdens on immunocompromised hosts
The duration for which they should be continued is not specified
Clinical Applications
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