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To be eligible patients must have: A Body Mass Index (BMI) of 40 or more AND Have been diagnosed with AT LEAST FOUR of the following: High blood pressure High cholesterol or abnormal blood fats Sleep apnoea Heart disease Type 2 diabetes For more details on who will become eligible over the coming years, see page 7 of the official NHS Guidance

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According to FDA prescribing information and clinical trial data, nausea is the most common adverse effect, occurring in 15-44% of patients depending on the specific medication and dose

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doi: 10.1136/bmj.g7607 203 HardingJLShawJEPeetersACartensenBMaglianoDJ

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B12 is deficient, homocysteine rises because vitamin B12 is a co-factor in a reaction catalysed by the enzyme methionine synthase in converting homocysteine into methionine

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Building a Reputation on Trust and Support FuturHealths growing popularity stems from more than just affordabilityits also about the digital-first care model that allows people to take charge of their health without the traditional barriers of scheduling, commuting, or navigating dense insurance policies

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