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The benefit for GLP-1-associated nausea specifically has not been studied in a controlled trial, but the mechanism (5-HT3 antagonism and gastric prokinetic effects) is consistent with potential benefit
Patients with a personal or family history of medullary thyroid carcinoma (MTC) or multiple endocrine neoplasia syndrome type 2 (MEN2) should not use this medication
These include semaglutide, liraglutide, dulaglutide, and tirzepatide
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Data extraction was carried out on study characteristics, participant demographics, interventions, and outcomes related to weight reduction, metabolic parameters, and side effects
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