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doi: 10.3390/nu12061798 135

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Ten-eleven Translocation (TET) enzymes converts methylcytosine (m 5 C) to hydroxymethylcytosine (hmC), which is not recognized by Dnmt1, it is believed to exclude maintenance methylation allowing for passive demethylation, and it is an intermediate in the active conversion of m 5 C to cytosine (C) 27

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It can be argued that significant effects were seen largely due to the homogeneous participant pool that started out with decreased metabolic health, and that results may not apply to healthy weight individuals