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Pilozzi A, Carro C, Huang X (2021) Roles of -endorphin in stress, behavior, neuroinflammation, and brain energy metabolism

While existing research has confirmed that dysregulated expression of copper transporters (such as ATP7A, CTR1) is a core mechanism inducing cellular cuproptosis in models of endothelial injury induced by disturbed blood flow ( Drawing upon the known property of exosomes to targetedly deliver bioactive molecules, we raise a speculative hypothesis: exosomes released by damaged endothelium might have the theoretical capacity to induce secondary cuproptosis responses in the vascular microenvironment, potentially by encapsulating abnormal copper transporters or cytotoxic lipoylated protein aggregates

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Springer, Dordrecht, pp 621655

Effects of heavy metals on ultrastructure and HSP70S Induction in the aquatic mossleptodictyum ripariumhedw