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For comparisons between two groups, normally distributed data with equal variances were analyzed using a two-tailed unpaired Students t-test, while non-normally distributed data or data with unequal variances were assessed using the Mann-Whitney U test

10.1007/s00441-019-03016-8 26 HedenstiernaG.LarssonA

A clinical review published in the International Journal of Molecular Sciences documenting the pharmacological basis and clinical applications of therapeutic peptides, confirming their classification as off-label compounded preparations outside FDA-approved indications provides the regulatory context

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In contrast, the oral CoQ10 group showed only slight improvements during the same period