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Qualora questo non fosse sufficiente per abbassare la glicemia, si ricorre alluso di metformina in monoterapia

This will require granular strategic patient segmentation informed by multiple data sources with RWD playing a key role, e.g., anonymised, longitudinal patient-level Rx data, claims data or EMR, combined with primary market research

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Furthermore, it provides a critical appraisal of recent human observational data, distinguishing metabolic benefits from intrinsic disease-modifying effects, and outlines the practical clinical friction points and prospective trials necessary to validate these pathways in future treatment paradigms

Grabowski, U, Behrends: Chronisches Fatigue-Syndrom/CFS rzteblatt Sachsen 9|2019 (2019), 26-30.