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Safety considerations for GLP-1 receptor agonist use in post-bariatric surgery patients require careful attention, as this population may have unique vulnerabilities and altered pharmacokinetics compared to patients without surgical history

Food and Drug Administration approved a once-daily oral version of Wegovy (semaglutide) in December 2025 for chronic weight management in adults meeting specific clinical criteria

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Response label creation The binary label for treatment responsiveness was created by the following method: the median HbA1C level within 12 months before GLP-1 M treatment was used as the pretreatment HbA1C