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Your healthcare provider considers your treatment goals, current health status, medication tolerance, and response to therapy when establishing and adjusting your dosing regimen

The linear peptide is covalently bound to a C20 fatty diacid moiety at the side chain of the Lys20 amino acid ( Figure 2 depicts the amino acid sequence of tirzepatide in comparison to GLP-1, GIP as well as the GLP-1RA exendin-4 (exenatide)

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Both triple and dual receptor agonists show similar enhancement of cAMP production in comparison to single GLP-1 receptor agonists [75]