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If left untreated, vitamin B12 deficiency can cause neurological changes, such as numbness or tingling in the hands and feet

Here is a summary of how topical GHK-Cu was administered in three select studies: In a 1998 study by Abdulghani et al., GHK-Cu was found to have a significant effect on collagen production when applied as a cream to the thigh area for one month

Here is a clear comparison to help you understand how each works and when one may be more appropriate

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10.1002/cbf.1245