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Phentermine is FDA-approved for weight loss and has been in active clinical use since 1959 making it one of the most studied weight loss medications available

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Conventional therapies like physical therapy, occupational therapy, and intravenous immunoglobulin remain important

The Endocrine Society's 2020 position statement on compounded hormones and peptides emphasizes that "compounded preparations should be used only when an FDA-approved product is not available or is not suitable for a particular patient" [12]

Emerging research directions include investigation of senescence heterogeneity and tissue-specific senescent cell populations, with FOXO4-DRI serving as a tool for studying how different senescent cell types contribute to various pathological processes