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There hasnt been a medical innovation thats been this impactful, really, since the advent of statins, Nunn said in a phone interview, referring to the cholesterol-lowering drugs that premiered in 1987 and were prescribed to an estimated 92 million Americans in 2018 and 2019

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But in general, turning a peptide (including GLP-1 or insulin) into an oral formulation means overcoming three major challenges: protecting the peptide from digestion in the stomach, improving absorption of the peptide via the gut, and slowing down the enzymatic breakdown and excretion of the peptide once it is in the blood