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Landmark 2017 Cell paper One of the foundational studies (by Baar et al.) was titled Targeted apoptosis of senescent cells restores tissue homeostasis in response to chemotoxicity and aging. This work demonstrated: In mice that were aged or given chemotherapy (accelerated ageing), treatment with FOXO4-DRI improved physical performance, fur quality, and renal function

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In high doses, garlic can affect the cytochrome P450 system, particularly one enzyme called cytochrome 2C9, a liver enzyme that helps process medications, including birth control hormones

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