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For the side effect phenotypes, we defined separate casecontrol phenotypes for each side effect recorded in the survey, contrasting those who self-rated their side effects as moderate or severe (cases) to those who self-rated their side effects as mild or non-existent (controls)
The 15mg dose produced 20.9% average weight loss, translating to approximately 48 lbs for someone starting at 231 lbs
Treatment Frequency : Space out treatments by 7-10 days to allow the body to process the released fat and minimize potential side effects
For those on newer medications like semaglutide and tirzepatide specifically, the regain was even steeper, averaging 9.69 kg
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