Engages brainstem and hypothalamic circuits (notably in the area postrema and related nuclei) to decrease food intake, increase satiety, slow gastric emptying, and ultimately lower body weight in animal and human studies
21: 206573 Data on file, Searle (Pharmacia), 2000 Roujeau J, Kelly J, Naldi L, et al
Oncogenic Potential (Cancer Risk) Both peptides encourage angiogenesis (blood vessel growth) and cell proliferation
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Abdulmughni LA, Al-Sanabani JA, Gilan WM, Issa MA, Jowah HM